In this paper, we focus on three locations in the Asia-Pacific region—Hong Kong, Shenzhen, and Singapore—to analyse the impact of variations in research and development (R&D) spending on total factor productivity (TFP) growth. In each of the three cases, we compare and contrast the role of public and private R&D in boosting TFP growth as well as the pattern of causality involving public and private R&D and the capacity of both types of R&D to generate economic spillovers.