In this paper, we focus on three locations in the Asia-Pacific region—Hong Kong, Shenzhen, and Singapore—to analyse the impact of variations in research and development (R&D) spending on total factor productivity (TFP) growth. In each of the three cases, we compare and contrast the role of public and private R&D in boosting TFP growth as well as the pattern of causality involving public and private R&D and the capacity of both types of R&D to generate economic spillovers.

Combining documentary analysis with hierarchical cluster analysis (HCA), we conduct a comparative study of innovation policies in two municipalities included in the Greater Bay Area (GBA) initiative—the Chinese government’s plan to link eleven cities into an economic and business hub. After identifying innovation policies/agencies in Hong Kong and Shenzhen, we apply the HCA to compare similarities and differences between their innovation policies and assess how these policies align with the ‘cross-border regional innovation system’ (CBRIS) conceptual approach.